Surface functionalization of mesoporous silica nanoparticles is important for their applications but fairly challenging using benzene-bridged organosilane as the precursor through the postsynthesis approach. Herein, we report an acid-catalysis approach for the postmodification of benzene-bridged organosilica onto the surface of large-pore mesoporous silica nanoparticles. By using HCl (∼1 M) as the acid catalyst in a tetrahydrofuran solvent, the self-assembly of the bridged organosilica precursor is avoided, while surface modification of mesoporous silica nanoparticles is promoted with controllable organic contents and retained large pore sizes. This strategy can also be applied to the postmodification of organosilica with end benzene groups. The strategy developed in this study is expected to be applied for the postmodification of other organosilica precursors with various functions.

中文翻译：

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苯桥有机硅改性的介孔二氧化硅纳米粒子的酸催化方法

介孔二氧化硅纳米颗粒的表面官能化对其应用很重要，但是通过后合成方法使用苯桥有机硅烷作为前体是相当具有挑战性的。在这里，我们报告了一种酸催化方法，用于将苯桥接的有机硅后改性到大孔介孔二氧化硅纳米粒子的表面上。通过在四氢呋喃溶剂中使用HCl（〜1 M）作为酸催化剂，可以避免桥接有机硅前体的自组装，同时以可控的有机物含量和较大的孔径促进介孔二氧化硅纳米粒子的表面改性。该策略也可用于带有末端苯甲酸酯基团的有机硅的后改性。