Listeria monocytogenes are pathogenic microorganisms and of particular concern in the poultry industry. They are frequently isolated from raw chicken products due to their ability to attach to a wide variety of food and food-contact surfaces. The application of synthetic antimicrobial agents is often limited by potential emergence of antimicrobial resistance and regulations associated to organic poultry products. Development of natural antimicrobial agents controlling Listeria monocytogenes contamination and pathogenesis represent an alternative approach. This study screened a range of plant extracts (including those from cranberry, mangosteen, persimmon, and roselle) for their ability to affect five Listeria monocytogenes strains with respect to their bacterial surface hydrophobicity, auto-aggregation, and attachment to cultured human colorectal cells. Results show that mangosteen extracts showed significant inhibitory effects on the attachment of Listeria monocytogenes to the cell line, potentially due to a high level of proanthocyanidin content. In addition, the plant extracts influenced bacterial auto-aggregation (increase in most of the cases) by increasing bacterial surface hydrophobicity. These results may support future development of alternative antimicrobial agents controlling the contamination and pathogenesis of Listeria monocytogenes.

中文翻译：

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由于原花青素含量高，山竹提取物可抑制鸡单核细胞增生李斯特菌分离株与培养的结直肠细胞的附着

单核细胞增生李斯特菌是病原微生物，在家禽业中受到特别关注。由于它们能够附着在各种食品和食品接触表面，因此它们经常与生鸡肉产品分离。合成抗菌剂的应用通常受到抗菌素耐药性的潜在出现和与有机家禽产品相关的法规的限制。开发控制单核细胞增生李斯特菌污染和发病机制的天然抗菌剂代表了一种替代方法。本研究筛选了一系列植物提取物（包括来自蔓越莓、山竹、柿子和洛神花的提取物）对五种单核细胞增生李斯特菌的影响能力菌株的细菌表面疏水性、自动聚集和与培养的人类结直肠细胞的附着。结果表明，山竹提取物对单核细胞增生李斯特菌对细胞系的附着有显着的抑制作用，这可能是由于原花青素含量高。此外，植物提取物通过增加细菌表面疏水性影响细菌自动聚集（在大多数情况下增加）。这些结果可能支持未来开发控制单核细胞增生李斯特菌污染和发病机制的替代抗菌剂。