Chikungunya virus (CHIKV) is a (re)emerging arbovirus and the causative agent of chikungunya fever. In recent years, CHIKV was responsible for a series of outbreaks, some of which had serious economic and public health impacts in the affected regions. So far, no CHIKV-specific antiviral therapy or vaccine has been approved. This review gives a brief summary on CHIKV epidemiology, spread, infection and diagnosis. It furthermore deals with the strategies against emerging diseases, drug development and the possibilities of testing antivirals against CHIKV in vitro and in vivo. With our review, we hope to provide the latest information on CHIKV, disease manifestation, as well as on the current state of CHIKV vaccine development and post-exposure therapy.

基孔肯雅病毒 (CHIKV) 是一种（重新）出现的虫媒病毒，是基孔肯雅热的病原体。近年来，CHIKV 引发了一系列疫情，其中一些疫情对受影响地区造成了严重的经济和公共卫生影响。迄今为止，尚无 CHIKV 特异性抗病毒疗法或疫苗获批。这篇综述简要总结了CHIKV的流行病学、传播、感染和诊断。它还涉及针对新兴疾病的策略、药物开发以及在体外和体内测试抗 CHIKV 抗病毒药物的可能性。通过我们的审查，我们希望提供有关 CHIKV、疾病表现以及 CHIKV 疫苗开发和暴露后治疗的现状的最新信息。