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Pyroptosis executive protein GSDMD as a biomarker for diagnosis and identification of Alzheimer’s disease
Brain and Behavior ( IF 3.1 ) Pub Date : 2021-02-15 , DOI: 10.1002/brb3.2063
Heping Shen 1 , Chenyang Han 2 , Yi Yang 2 , Li Guo 3 , Yongjia Sheng 2 , Jin Wang 2 , Wenyan Li 2 , Liping Zhai 1 , Genghuan Wang 1 , Qiaobing Guan 1
Affiliation  

This study was mainly conducted to explore the expression changes of GSDMD and conventional markers (including T‐Tau, Tau181p, and Aβ1–42) in the cerebrospinal fluid among patients with Alzheimer's disease (AD) and vascular dementia (VD), followed by determination of role of GSDMD in diagnosing and identifying AD and VD.

中文翻译:

焦亡执行蛋白 GSDMD 作为阿尔茨海默病诊断和鉴定的生物标志物

本研究主要探讨阿尔茨海默病(AD)和血管性痴呆(VD)患者脑脊液中GSDMD和常规标志物(包括T-Tau、Tau181p和Aβ1-42 )的表达变化,其次是确定 GSDMD 在诊断和识别 AD 和 VD 中的作用。
更新日期:2021-04-11
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