This study evaluated the effects of walking exercise and nutritional plan on metabolic variables and the growth of stabled goats. Thirty-six goats [body weight (BW) = 21 ± 0.3 kg] were allocated in individual pens, and the treatments were randomly assigned to the animals in a 2 × 2 factorial design. The treatments consisted of walking exercise (7,5 km/day) or not and two nutritional plans [90 % (0.9M) or 170 % (1.7M) of the maintenance requirements] for 50 days (first period) . Further, all animals were fed a diet that met 170 % of their maintenance requirements and were not subjected to exercise for more 35 days (second period). There was no interaction effect between walking and nutritional plan for any of the studied variables. Walking exercise did not affect rib-eye area (REA; P = 0.13) or subcutaneous fat thickness (SFT; P = 0.11), but reduced body weight (BW) in the first (P = 0.03) and second (P = 0.03) periods. The animals in the 0.9M nutritional plan group exhibited lower REA and SFT values than those in the 1.7M group. This was accompanied by a decrease in plasma triiodothyronine concentration (T₃; P = 0.03) in the animals that received the 0.9M plan in the first period. Exercise and nutritional plan, respectively, did not change (P ≥ 0.17) the plasma concentration of growth hormone (P = 0.31; P = 0.17), the gene expression of growth hormone receptors (GHR; P = 0.85; P = 0.79), insulin-like growth factor 1 (IGF-I; P = 0.87; P = 0.77), insulin-like growth factor 1 receptor (IGF1R; P = 0.55; P = 0.63) or peroxisome proliferator-activated receptors alpha (PPARα; P = 0.90; P = 0.92). In the second period, the BW and REA of the goats in the 0.9M group remained lower than those observed in the 1.7M group (23.33 vs. 30.37; P < 0.0001). Plasma T₃ levels returned to values similar to those obtained with the 1.7M plan at the end of the second period (1.20 vs. 1.23; P = 0.03). Walking reduces the BW of goats without changing rib-eye area, subcutaneous fat deposition on the Longissimus muscle or gene expression. Nutritional restriction through a diet that meets 90 % of the maintenance requirements reduces weight gain but does not induce a full compensatory growth in goats.

这项研究评估了步行运动和营养计划对代谢变量和稳定山羊生长的影响。将三十六只山羊[体重（BW）= 21±0.3公斤]分配到每只围栏中，并按2×2因子设计将处理随机分配给动物。治疗包括50天内（第一阶段）进行步行运动（是否进行7.5公里/天）和两项营养计划[维持需求的90％（0.9M）或170％（170M））。进一步，所有动物的饮食均达到其维持要求的170％，并且在超过35天（第二期）内均未进行运动。对于任何研究变量，步行与营养计划之间没有交互作用。步行运动不会影响肋眼区域（REA; P = 0.13）或皮下脂肪厚度（SFT; P = 0.11），但在第一（P = 0.03）和第二（P = 0.03）中体重减轻（BW）。期。营养计划为0.9M的动物，其REA和SFT值低于1.7M的动物。这伴随着血浆三碘甲状腺素浓度的降低（T ₃; 在第一阶段接受0.9M计划的动物中，P = 0.03）。运动和营养计划分别没有改变（P≥0.17）生长激素的血浆浓度（P = 0.31; P = 0.17），生长激素受体的基因表达（GHR; P = 0.85; P = 0.79），胰岛素样生长因子1（IGF-1; P = 0.87; P = 0.77），胰岛素样生长因子1受体（IGF1R; P = 0.55; P = 0.63）或过氧化物酶体增殖物激活受体α（PPARα; P = 0.90； P = 0.92）。在第二阶段，0.9M组山羊的BW和REA仍然低于1.7M组中的山羊的BW和REA（23.33对30.37； P <0.0001）。血浆T ₃值返回到与第二个周期结束时使用1.7M计划获得的值相似的值（1.20对1.23； P = 0.03）。步行可降低山羊的体重，而不会改变肋眼面积，在Longissimus肌肉上的皮下脂肪沉积或基因表达。通过满足90％维持要求的饮食进行营养限制可以减少体重增加，但不会引起山羊的完全代偿性生长。