Lemon balm (Melissa officinalis L.) is a popular herb used as an aromatic and medicinal resource as well as a herbal tea. Due to a lack of information on the hydroponic growth of lemon balm, three hydroponic systems (artificial soil bed, perlite bed, and aeroponic) that could be applied to industrial production were tested in the present study. In this context, the growth parameters, mineral contents, color traits, anti-oxidative capacities, and phenolic compounds of lemon balm were analyzed. As a result, the three types of systems assessed showed similar yields and even compared to previous studies. However, the soilless cultivation system (perlite and aeroponic) showed increased nitrate content but decreased the chlorine mineral content. In addition, they showed lowered total phenolic acid content and radical scavenging capacity, which was associated with decreased rosmarinic acid and lithospermic acid A, the major phenolic compounds in lemon balm. Conversely, the caffeic acid and methyl rosmarinate content increased by 6–8 times in soilless cultivation system compared to soil-based conditions. In conclusion, the hydroponic cultivation methods used in this study could be applied to the industrial production of lemon balm with yields and qualities consistent with traditional growth conditions. In addition, soilless hydroponic systems could be used to produce specified lemon balm rich in caffeic acid and methyl rosmarinate.

柠檬香脂（梅利莎厚朴L.）是一种流行的草药，可用作芳香和药用资源以及凉茶。由于缺乏有关香蜂草水培生长的信息，因此在本研究中测试了可用于工业生产的三种水培系统（人工土壤床，珍珠岩床和航空设备）。在这种情况下，分析了柠檬香脂的生长参数，矿物质含量，颜色特征，抗氧化能力和酚类化合物。结果，评估的三种类型的系统显示出相似的产量，甚至与以前的研究相比。但是，无土栽培系统（珍珠岩和气培）的硝酸盐含量增加，但氯矿物质含量降低。此外，它们还降低了总酚酸含量和自由基清除能力，这与迷迭香脂和柠檬精中的主要酚类化合物迷迭香酸和紫精酸A含量降低有关。相反，与基于土壤的条件相比，在无土栽培系统中，咖啡酸和迷迭香酸甲酯的含量增加了6-8倍。总之，本研究中使用的水培栽培方法可用于柠檬香脂的工业生产，其产量和品质与传统生长条件一致。此外，无土的水耕系统可用于生产富含咖啡酸和迷迭香酸甲酯的特定柠檬香脂。本研究中使用的水培栽培方法可用于柠檬香脂的工业生产，其产量和品质与传统生长条件一致。此外，无土的水耕系统可用于生产富含咖啡酸和迷迭香酸甲酯的特定柠檬香脂。本研究中使用的水培栽培方法可用于柠檬香脂的工业生产，其产量和品质与传统生长条件一致。此外，无土的水耕系统可用于生产富含咖啡酸和迷迭香酸甲酯的特定柠檬香脂。