Among 170 adults with sickle cell disease, we evaluated chronic pain impact and disability prevalence, assessed age and gender differences, and identified psychosocial predictors of chronic pain intensity and disability. Most participants had a high level of disability. Chronic pain intensity and disability were significantly associated with pain catastrophizing and chronic pain self-efficacy, and worsened with age. Further research is needed to confirm study findings and develop interventions, including palliative care approaches that address catastrophizing and disability, particularly for young women and middle-aged adults with sickle cell disease. Moreover, consistent clinical assessment of chronic pain and psychosocial health should be implemented.

中文翻译：

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成人镰状细胞病患者慢性疼痛强度和残疾的患病率和预测因素

在170名患有镰状细胞病的成人中，我们评估了慢性疼痛的影响和残疾患病率，评估了年龄和性别差异，并确定了慢性疼痛强度和残疾的社会心理预测因子。大多数参与者的残疾程度很高。慢性疼痛强度和残疾与灾难性疼痛和慢性疼痛自我效能感显着相关，并且随着年龄的增长而恶化。需要进一步的研究以确认研究结果并制定干预措施，包括应对灾难性和残疾的姑息治疗方法，特别是对于患有镰状细胞病的年轻妇女和中年成年人。此外，应实施对慢性疼痛和社会心理健康的一致临床评估。