Introduction Concussion is a clinical diagnosis, based on self-reported patient symptoms supported by clinical assessments across many domains including postural control, ocular/vestibular dysfunction, and neurocognition. Concussion incidence may be rising in motorsport which, combined with unresolved challenges to accurate diagnosis and lack of guidance on the optimal return-to-race timeframe, creates a difficult environment for healthcare practitioners. Methods and analysis Research Evaluating Sports ConcUssion Events—Rapid Assessment of Concussion and Evidence for Return (RESCUE-RACER) evaluates motorsports competitors at baseline (Competitor Assessment at Baseline; Ocular, Neuroscientific (CArBON) study) and post-injury (Concussion Assessment and Return to motorSport (CARS) study), including longitudinal data. CArBON collects pre-injury neuroscientific data; CARS repeats the CArBON battery sequentially during recovery for competitors involved in a potentially concussive event. As its primary outcome, RESCUE-RACER will develop the evidence base for an accurate trackside diagnostic tool. Baseline objective clinical scoring (Sport Concussion Assessment Tool—5th edition (SCAT5)) and neurocognitive data (Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT)) will be assessed for specificity to motorsport and relationship to existing examinations. Changes to SCAT5 and ocular, vestibular, and reaction time function (Dx 100) will be estimated by the reliability change index as a practical tool for trackside diagnosis. Neuropsychological (Cambridge Neuropsychological Test Automated Battery (CANTAB)) assessments, brain MRI (7 Tesla) and salivary biomarkers will be compared with the new tool to establish utility in diagnosing and monitoring concussive injuries. Ethics and dissemination Ethical approval was received from East of England-Cambridge Central Research Ethics Committee (18/EE/0141). Participants will be notified of study outcomes via publications (to administrators) and summary reports (funder communications). Ideally, all publications will be open access. Trial registration number February 2019 nationally (Central Portfolio Management System 38259) and internationally (ClinicalTrials.gov [NCT03844282][1]). [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03844282&atom=%2Fbmjosem%2F7%2F1%2Fe000879.atom

中文翻译：

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评价体育震荡事件的研究—震荡和返回证据的快速评估（RESCUE-RACER）：一项为期两年的纵向震荡观察研究

简介脑震荡是一种临床诊断，基于自我报告的患者症状，并在许多方面进行了临床评估，包括姿势控制，眼/前庭功能障碍和神经认知。赛车运动中脑震荡的发生率可能会上升，再加上准确诊断未解决的挑战以及对最佳竞赛时间框架缺乏指导的情况，给医疗从业人员带来了艰难的环境。方法和分析研究体育震荡事件的研究-脑震荡和返回证据的快速评估（RESCUE-RACER）在基线时评估赛车比赛的竞争对手（在基线时进行的竞争对手评估；在眼科学，神经科学（CArBON）的研究中）和在受伤后进行的研究（脑震荡评估和返回）进行赛车运动（CARS）研究），包括纵向数据。CArBON收集损伤前的神经科学数据；在恢复过程中，CARS会为可能引起脑震荡事件的竞争对手依次重复使用CArBON电池。作为其主要成果，RESCUE-RACER将为准确的路边诊断工具开发证据基础。将评估基线客观临床评分（运动脑震荡评估工具，第5版（SCAT5））和神经认知数据（立即脑震荡评估和认知测试（ImPACT））对赛车运动的特异性以及与现有检查的关系。SCAT5以及眼，前庭和反应时间函数（Dx 100）的变化将通过可靠性变化指数（作为路边诊断的实用工具）进行估算。神经心理学（剑桥神经心理学自动测试电池（CANTAB））评估，大脑MRI（7特斯拉）和唾液生物标记物将与新工具进行比较，以建立诊断和监测脑震荡损伤的效用。道德与传播道德从英格兰东部剑桥中央研究道德委员会获得批准（18 / EE / 0141）。研究成果将通过出版物（向管理者）和摘要报告（欺诈性通讯）通知参加者。理想情况下，所有出版物都是开放获取的。国家（中央项目组合管理系统38259）和国际（ClinicalTrials.gov [NCT03844282] [1]）的注册号为2019年2月。[1]：/lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03844282&atom=%2Fbmjosem%2F7%2F1%2Fe000879.atom 道德与传播道德从英格兰东部剑桥中央研究道德委员会获得批准（18 / EE / 0141）。研究成果将通过出版物（向管理者）和摘要报告（欺诈性通讯）通知参加者。理想情况下，所有出版物都是开放获取的。国家（中央项目组合管理系统38259）和国际（ClinicalTrials.gov [NCT03844282] [1]）的注册号为2019年2月。[1]：/lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03844282&atom=%2Fbmjosem%2F7%2F1%2Fe000879.atom 道德与传播道德从英格兰东部剑桥中央研究道德委员会获得批准（18 / EE / 0141）。研究成果将通过出版物（向管理者）和摘要报告（欺诈性通讯）通知参加者。理想情况下，所有出版物都是开放获取的。国家（中央项目组合管理系统38259）和国际（ClinicalTrials.gov [NCT03844282] [1]）的注册号为2019年2月。[1]：/lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03844282&atom=%2Fbmjosem%2F7%2F1%2Fe000879.atom 所有出版物均为开放获取。国家（中央项目组合管理系统38259）和国际（ClinicalTrials.gov [NCT03844282] [1]）的注册号为2019年2月。[1]：/lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03844282&atom=%2Fbmjosem%2F7%2F1%2Fe000879.atom 所有出版物均为开放获取。国家（中央项目组合管理系统38259）和国际（ClinicalTrials.gov [NCT03844282] [1]）的注册号为2019年2月。[1]：/lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03844282&atom=%2Fbmjosem%2F7%2F1%2Fe000879.atom