Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndromerelated coronavirus-2 (SARS-CoV-2), has become an ongoing pandemic worldwide. However, there are no vaccines or antiviral drugs with proven clinical efficacy. Therefore, a remedial measure is urgently needed to combat the devastating COVID-19. The pharmacological activities of Nacetylcysteine (NAC) and its potential functions in inhibiting the progression of COVID-19 make it a promising therapeutic agent for the infection. In this mini-review, we discussed the therapeutic potential of NAC in COVID-19 from the perspective of its multisite pharmacological actions.

由严重急性呼吸系统综合症相关冠状病毒2（SARS-CoV-2）引起的冠状病毒病2019（COVID-19）已成为全球持续流行的疾病。但是，没有疫苗或抗病毒药物具有被证明的临床疗效。因此，迫切需要采取补救措施来抵抗毁灭性的COVID-19。N乙酰半胱氨酸（NAC）的药理活性及其在抑制COVID-19进程中的潜在功能使其成为感染的有前途的治疗剂。在此小型审查中，我们从多部位药理作用的角度讨论了NAC在COVID-19中的治疗潜力。