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Activation of Nanocomposite Liposomal Capsules in a Conductive Water Medium by Ultra-Short Electric Exposure
Journal of Communications Technology and Electronics ( IF 0.5 ) Pub Date : 2021-02-10 , DOI: 10.1134/s1064226921010022
Yu. V. Gulyaev , V. A. Cherepenin , I. V. Taranov , V. A. Vdovin , G. B. Khomutov

In a system that simulates aquatic biological media, the possibility of activating nanocomposite liposomal capsules (NLCs) containing spherical electrically conductive nanoparticles on the outer and inner surfaces of the liposomal membrane, using an external ultrashort electric action, has been shown. The decapsulation effect was registrated by fluorimetry methods. The key role of conducting nanoparticles in increasing the sensitivity of NLCs to external ultrashort electrical impact is shown. A theoretical model of nonthermal interaction of NLCs with ultrashort electric pulses is constructed, within the frame of which an expression is obtained for the critical value of the electric field strength, which determines the threshold for the appearance of the decapsulation effect in a conducting medium. The described mechanism of decapsulation explains the selective nature of ultrashort pulsed electrical impact on the NLCs.



中文翻译:

通过超短时电暴露活化水介质中的纳米复合脂质体胶囊。

在模拟水生生物介质的系统中,已经显示了使用外部超短电作用激活脂质体膜外表面和内表面上包含球形导电纳米粒子的纳米复合脂质体胶囊(NLC)的可能性。解封效果通过荧光法记录。显示了导电纳米粒子在增加NLC对外部超短电冲击的敏感性中的关键作用。构建了NLC与超短电脉冲的非热相互作用的理论模型,在该模型的框架内获得了电场强度临界值的表达式,该表达式确定了在导电介质中出现解封装效应的阈值。

更新日期:2021-02-10
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