Distribution of arsenic (As) in tissues and gonads of the Indo-Pacific sailfish Istiophorus platypterus and the dolphinfish Coryphaena hippurus from the SE Gulf of California was evaluated. The bioaccumulation patterns of As were the same in the two species. In I. platypterus, As levels (mg kg⁻¹, wet weight) were gonads (7.4 ± 1.1) > liver (3.1 ± 0.1) > kidney (2.7 ± 0.1) > muscle (1.6 ± 0.1); in C. hippurus, As (mg kg⁻¹) levels were gonads (4.3 ± 0.6) > liver (3.2 ± 0.2) > kidney (2.3 ± 0.1) > muscle (1.2 ± 0.1). Differences in As distribution could be attributed to the biological functions of tissues. The hypothesis was confirmed that biomagnification was evidenced by the fact that As levels were lower in prey species than in predators. Intake of muscle from either fish did not represent a risk to humans if recommended portions a week are not exceeded, adults as much as 1802.4 g and 2454.1 g and children 257.5 and 350.6 g, for sailfish and dolphinfish, respectively. In addition, the likelihood of developing cancer due to consumption of edible tissues from either of these top predators was in the acceptable range (6.4 × 10⁻⁵ to 27.3 × 10⁻⁶ for a population that consumes 50 g of muscle in a week) but if a conservative combined slope factor is used the probabilities to develop bladder and lung cancer increments from 1.1 × 10⁻³ to 9.1 × 10⁻⁵.

评估了来自加利福尼亚州东南部的印度-太平洋旗鱼Istiophorus platypterus和海豚Coryphaena hippurus组织和性腺中砷 (As) 的分布。As的生物累积模式在两个物种中是相同的。在I. platypterus中，As 水平（mg kg ^-1，湿重）为性腺 (7.4 ± 1.1) > 肝脏 (3.1 ± 0.1) > 肾脏 (2.7 ± 0.1) > 肌肉 (1.6 ± 0.1)；在C. hippurus中，As (mg kg ^-1) 水平为性腺 (4.3 ± 0.6) > 肝脏 (3.2 ± 0.2) > 肾脏 (2.3 ± 0.1) > 肌肉 (1.2 ± 0.1)。As 分布的差异可归因于组织的生物学功能。这一假设得到证实，生物放大作用的证据是猎物物种中的砷水平低于捕食者。如果不超过每周建议的摄入量，从这两种鱼中摄入的肌肉对人类没有风险，旗鱼和海豚的成人分别高达 1802.4 克和 2454.1 克，儿童分别为 257.5 和 350.6 克。此外，由于食用这些顶级捕食者的可食用组织而患癌症的可能性在可接受的范围内（6.4 × 10 ^-5至 27.3 × 10 ^-6对于每周消耗 50 g 肌肉的人群），但如果使用保守的组合斜率因子，则患膀胱癌和肺癌的概率从 1.1 × 10 ^-3增加到 9.1 × 10 ^-5。