ABSTRACT

Background: To assess the impact of our surgical strategy for the treatment of patients with functional single ventricle and pulmonary hypertension, especially in patients>24 months old.

Methods We retrospectively analyzed the clinical data of 97 patients with functional single ventricle and pulmonary hypertension undergoing pulmonary artery banding (PAB) in our hospital between April 2010 and December 2018. The surgical results, transition to Glenn operation and subsequent transition to Fontan operation were analyzed.

Results: The 97 patients underwent PAB included 34 patients>24 months old, hospital mortality was 2.1% (2/97). 62 patients underwent the second-stage Glenn operation, and 21 patients underwent third-stage Fontan operation. On competing risk analysis, at 80 months after PAB, 81% had undergone the Glenn operation, and 13% were awaiting the Glenn operation. At 35 months after the Glenn operation, 2% of patients had died, 63% had undergone the Fontan operation, and 36% were awaiting the Fontan operation.

Conclusion: PAB is an acceptable strategy for patients with functional single ventricle associated with pulmonary hypertension. Outcomes and results of subsequent Glenn and Fontan procedures are generally good included patients>24 months. Accompanied with unbalanced atrioventricular septal defect for lower ratio of transition to Glenn and Fontan operation.

摘要

背景：评估我们的手术策略对功能性单心室和肺动脉高压患者的治疗效果，尤其是对> 24个月大的患者。

方法回顾性分析2010年4月至2018年12月在我院接受肺动脉束缚带（PAB）治疗的97例功能性单心室和肺动脉高压患者的临床资料。 。

结果： 97例行PAB的患者包括34例> 24个月大的患者，住院死亡率为2.1％（2/97）。62例接受了第二期Glenn手术，21例接受了第三期Fontan手术。根据竞争风险分析，PAB后80个月，有81％的人进行了Glenn手术，另有13％的人在等待Glenn手术。Glenn手术后35个月，有2％的患者死亡，63％的患者接受了Fontan手术，而36％的患者正在等待Fontan手术。

结论：对于患有肺动脉高压的功能性单心室患者，PAB是一种可接受的策略。包括> 24个月的患者，随后的Glenn和Fontan手术的结果和结果总体良好。伴有不平衡的房间隔缺损，可降低向Glenn和Fontan手术的过渡率。