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Effects of epigallocatechin gallate incorporation in UHMWPE on biological behavior, oxidative degradation, mechanical and tribological performance for biomedical applications
Tribology International ( IF 6.2 ) Pub Date : 2021-02-05 , DOI: 10.1016/j.triboint.2021.106887
Xueqin Kang , Xiaohui Zong , Peng Zhang , Xiao Zeng , Yu Liu , Chi Yao , Tao Wang , Peizhong Feng , Chunmin Yang

Oxidation of ultrahigh-molecular-weight-polyethylene (UHMWPE) affects its physicochemical properties. Epigallocatechin gallate (EGCG) was added to improve UHMWPE antioxidant capacity. The extract of UHMWPE stabilized with EGCG (EGCG/UHMWPE) exhibits cytocompatibility and cell viability in vitro. The gamma irradiated UHMWPE and EGCG/UHMWPE present similar physicochemical properties. Mechanical and tribological properties of irradiated pure UHMWPE are deteriorated after accelerated aging, while these properties are maintained after adding EGCG. The wear mechanism of irradiated UHMWPE is mainly abrasive and fatigue wear after accelerated aging, while the addition of EGCG improves the fatigue resistance and reduces the number of flakes and ruptures of irradiated UHMWPE.



中文翻译:

表没食子儿茶素没食子酸酯掺入超高分子量聚乙烯对生物医学应用的生物学行为,氧化降解,机械和摩擦学性能的影响

超高分子量聚乙烯(UHMWPE)的氧化会影响其理化性质。加入表没食子儿茶素没食子酸酯(EGCG)以提高UHMWPE的抗氧化能力。EGCG稳定的UHMWPE提取物(EGCG / UHMWPE)在体外具有细胞相容性和细胞活力。伽马射线辐照的UHMWPE和EGCG / UHMWPE具有相似的理化性质。加速老化后,辐照的纯UHMWPE的机械和摩擦学性能会下降,而添加EGCG后,这些性能会保持不变。辐照的UHMWPE的磨损机理主要是加速老化后的磨损和疲劳磨损,而添加EGCG可以提高抗疲劳性并减少辐照的UHMWPE的剥落和断裂数量。

更新日期:2021-02-09
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