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Aggregation-Induced Emission Fluorescent Gels: Current Trends and Future Perspectives
Topics in Current Chemistry ( IF 8.6 ) Pub Date : 2021-02-05 , DOI: 10.1007/s41061-020-00322-6
Javad Tavakoli 1 , Amin Jamshidi Ghahfarokhi 2 , Youhong Tang 2
Affiliation  

The development of fluorescent gels, if not the current focus, is at the center of recent efforts devoted to the invention of a new generation of gels. Fluorescent gels have numerous properties that are intrinsic to the gel structure, with additional light-emitting properties making them attractive for different applications. This review focuses on current studies associated with the development of fluorescent gels using aggregation-induced emission fluorophores (AIEgens) to ultimately suggest new directions for future research. Here, we discuss major drawbacks of the methodologies used frequently for the fabrication of fluorescent gels using traditional fluorophores compared to those using AIEgens. The fabrication strategies to develop AIE-based fluorescent gels, including physical mixing, soaking, self-assembly, noncovalent interactions, and permanent chemical reactions, are discussed thoroughly. New and recent findings on developing AIE-active gels are explained. Specifically, physically prepared AIE-based gels including supramolecular, ionic, and chemically prepared AIE-based gels are discussed. In addition, the intrinsic fluorescent properties of natural gels, known as clustering-triggered fluorescent gel, and new and recent relevant findings published in peer-reviewed journals are explained. This review also revealed the biomedical applications of AIE-based fluorescent hydrogels including drug delivery, biosensors, bioimaging, and tissue engineering. In conclusion, the current research situation and future directions are identified.



中文翻译:

聚集诱导的发射荧光凝胶:当前趋势和未来展望

荧光凝胶的开发,如果不是当前的重点,则是致力于新一代凝胶发明的最新努力的中心。荧光凝胶具有凝胶结构固有的众多特性,并具有额外的发光特性,使其对于不同的应用具有吸引力。这篇综述着重于与使用聚集诱导发射荧光团(AIEgens)开发荧光凝胶有关的当前研究,以最终为未来的研究提出新的方向。在这里,我们讨论与使用AIEgens相比,使用传统荧光团制造荧光凝胶经常使用的方法学的主要缺点。开发基于AIE的荧光凝胶的制备策略,包括物理混合,浸泡,自组装,非共价相互作用,和永久性化学反应,将进行彻底讨论。解释了开发AIE活性凝胶的最新发现。具体地,讨论了包括超分子,离子和化学制备的基于AIE的凝胶的物理制备的基于AIE的凝胶。此外,还解释了天然凝胶的固有荧光特性(称为簇触发荧光凝胶)以及在同行评审期刊上发表的新近相关发现。这篇综述还揭示了基于AIE的荧光水凝胶的生物医学应用,包括药物输送,生物传感器,生物成像和组织工程。总之,确定了当前的研究现状和未来方向。讨论了物理制备的基于AIE的凝胶,包括超分子,离子和化学制备的基于AIE的凝胶。此外,还解释了天然凝胶的固有荧光特性(称为簇触发荧光凝胶)以及在同行评审期刊上发表的新近相关发现。这篇综述还揭示了基于AIE的荧光水凝胶的生物医学应用,包括药物输送,生物传感器,生物成像和组织工程。总之,确定了当前的研究现状和未来方向。讨论了物理制备的基于AIE的凝胶,包括超分子,离子和化学制备的基于AIE的凝胶。此外,还解释了天然凝胶的固有荧光特性(称为簇触发荧光凝胶)以及在同行评审期刊上发表的新近相关发现。这篇综述还揭示了基于AIE的荧光水凝胶的生物医学应用,包括药物输送,生物传感器,生物成像和组织工程。总之,确定了当前的研究现状和未来方向。并解释了在同行评审期刊上发表的新近研究成果。这篇综述还揭示了基于AIE的荧光水凝胶的生物医学应用,包括药物输送,生物传感器,生物成像和组织工程。总之,确定了当前的研究现状和未来方向。并解释了在同行评审期刊上发表的新近相关发现。这篇综述还揭示了基于AIE的荧光水凝胶的生物医学应用,包括药物输送,生物传感器,生物成像和组织工程。总之,确定了当前的研究现状和未来方向。

更新日期:2021-02-05
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