A multicomponent thermal multi-relaxation-time (MRT) lattice Boltzmann method (LBM) is presented to study collapsing cavitation bubble. The simulation results satisfy Laplace law and the adiabatic law, and are consistent with the numerical solution of the Rayleigh–Plesset equation. To study the effects of the non-condensable gas inside bubble on collapsing cavitation bubble, a numerical model of single spherical bubble near a solid wall is established. The temperature and pressure evolution of the two-component two-phase flow are well captured. In addition, the collapse process of the cavitation bubble is discussed elaborately by setting the volume fractions of the gas and vapor to be the only variables. The results show that the non-condensable gas in the bubble significantly affects the pressure field, temperature field evolution, collapse velocity, and profile of the bubble. The distinction of the pressure and temperature on the wall after the second collapse becomes more obvious as the non-condensable gas concentration increases.