Increased demand for monitoring and identification of novel and unknown fluorinated compounds (FCs) has demonstrated the need of sensitive fluorine-specific detectors for unknown FCs in both biological and environmental matrices. Inductively coupled plasma mass spectrometry (ICP-MS) is a promising technique for analysis of FCs and has been rated as the most powerful tool in analytical chemistry. However, direct determination of fluorine using this technique is challenged by high ionization potential of fluorine together with spectral and nonspectral interferences which affect the quality of results. To enhance the quality of results, several studies have reported modifications of a conventional ICP-MS analysis procedure on sample preparation, introduction, analysis, and instrument optimization. Therefore, the focus of this study is to discuss different ICP-MS optimizations and future trends towards the effective analysis of FCs using ICP-MS.

中文翻译：

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使用电感耦合等离子体质谱法（ICP-MS）进行含氟化合物有效分析的趋势

监测和鉴定新型和未知氟化物（FC）的需求不断增加，这表明对生物和环境基质中未知FC的灵敏的氟特异性检测器的需求。电感耦合等离子体质谱法（ICP-MS）是一种用于分析FC的有前途的技术，并被认为是分析化学中最强大的工具。但是，使用这种技术直接测定氟受到氟的高电离势以及影响结果质量的光谱和非光谱干扰的挑战。为了提高结果的质量，几项研究报告了对常规ICP-MS分析程序的修改，包括样品制备，引入，分析和仪器优化。因此，