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Fully room temperature and label free biosensing based on an ink-jet printed polymer microdisk laser
Optical Materials Express ( IF 2.8 ) Pub Date : 2021-02-03 , DOI: 10.1364/ome.415000
Abdul Nasir , Yuya Mikami , Rui Yatabe , Hiroaki Yoshioka , Nilesh Vasa , Yuji Oki

Materials with biomolecule-compatible functional groups are desirable for the fabrication of microdisk lasers used in bio-sensing applications. In this study, a microdisk laser was fabricated using a low-viscosity hyper branched polymer FC-V-50 using ink-jet printing, and was surface-modified at room temperature within a relatively short time compared to conventional methods. The carboxyl functional group of the FC-V-50 polymer was used for surface modification and biotinylation. The adsorption characteristics of the microdisk laser were evaluated using bovine serum albumin, avidin, and streptavidin. This study reports the first demonstration of label-free biosensing using the FC-V-50 polymer-based microdisk laser.

中文翻译:

基于喷墨印刷聚合物微盘激光器的全室温和无标签生物传感

具有生物分子相容性官能团的材料对于制造用于生物传感应用中的微盘激光器是合乎需要的。在这项研究中,使用低粘度超支化聚合物FC-V-50通过喷墨印刷制造了微盘激光器,与传统方法相比,该激光器在室温下在较短的时间内进行了表面改性。FC-V-50聚合物的羧基官能团用于表面改性和生物素化。使用牛血清白蛋白,抗生物素蛋白和链霉亲和素评估微盘激光器的吸附特性。这项研究报告了首次使用基于FC-V-50聚合物的微盘激光器进行无标记生物传感的演示。
更新日期:2021-03-01
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