In the present study, graphite oxide, graphite oxide doped with 0.8 g AgNO₃ named GrO-0.5Ag, and graphite oxide doped with 1.25 g AgNO₃ named GrO-1.0Ag (silver-doped graphitic materials) were synthesized by the modified Hummers and chemical doping methods. Subsequently, its antimicrobial activity against Bacillus subtilis, Candida albicans, Escherichia coli, and Staphylococcus aureus microorganisms was evaluated by agar well diffusion test with 1 and 2 mg·ml⁻¹ of material concentrations. The silver-doped graphitic materials were characterized by X-Ray Diffraction, Fourier-Transform Infrared, Raman, X-Ray Photoelectron spectroscopies, and Scanning Electron Microscopy. The GrO-0.5Ag material showed a percentage of inhibition effect of 86, 82, 48, and 45% with respect to the positive control for Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Candida albicans microorganisms, respectively. Otherwise, the GrO-1.0Ag material showed a percentage of inhibition effect of 54% with respect to the positive control for Bacillus subtilis and less than 50% for the other microorganisms. The material concentrations showed a slight change in the percentage of inhibition effect for all microorganisms. Graphite oxide functional groups, small crystal size, free silver ions, and silver carbonate formation in silver-doped graphitic materials presented a viable alternative to inhibit bacterial growth.

在本研究中，通过改良的悍马（Hummers）合成了氧化石墨，掺杂有0.8 g AgNO _3的氧化石墨（称为GrO-0.5Ag）和掺杂有1.25 g AgNO ₃的氧化石墨（银掺杂石墨材料）。化学掺杂方法。随后，通过琼脂孔扩散试验以1和2 mg·ml ^-1的琼脂孔扩散试验评估其对枯草芽孢杆菌，白色念珠菌，大肠杆菌和金黄色葡萄球菌微生物的抗菌活性。物质浓度。通过X射线衍射，傅立叶变换红外，拉曼，X射线光电子能谱和扫描电子显微镜对银掺杂的石墨材料进行表征。相对于金黄色葡萄球菌，枯草芽孢杆菌，大肠杆菌和白色念珠菌的阳性对照，GrO-0.5Ag材料显示出分别为86％，82％，48％和45％的抑制效果。否则，相对于枯草芽孢杆菌的阳性对照，GrO-1.0Ag材料显示出54％的抑制作用而其他微生物的含量不到50％。物质浓度显示出对所有微生物的抑制作用百分比略有变化。在掺杂银的石墨材料中，氧化石墨官能团，较小的晶体尺寸，游离的银离子和碳酸银的形成是抑制细菌生长的可行选择。