Development of green nanotechnology has attracted significant attention of researchers towards the eco-friendly green synthesis of nanoparticles. The present study reports a green synthesis of copper oxide nanoparticles (CuO NPs) using the aqueous leaf extract of Cinnamomum malabatrum in appropriate conditions. It is observed that the leaf extract can act as reducing and stabilizing agents to synthesize CuO NPs. The synthesized NPs are characterized using XRD. The XRD pattern clearly suggests the crystalline nature and monoclinic structure of the synthesized composition. The average crystalline size is calculated using Debye-Scherrer relation and it was found to be 17nm. The FT-IR analysis is carried out in order to investigate the biomolecules present in the synthesized CuO NPs. The presence of CuO NPS is confirmed with EDX. The TEM and SEM images reveal the spherical shape of the NPs and the size of the NPs calculated is consistent with XRD results. The antibacterial activity of these NPs is tested against four human pathogenic bacteria both Gram-positive (S.aureus) and Gram-negative (E.coli, P.aeruginosa, and P.mirabilis). The synthesized CuO NPs show significant antibacterial activity against all the four bacteria.

中文翻译：

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肉桂叶提取物绿色合成氧化铜纳米粒子及其抗菌活性

绿色纳米技术的发展吸引了研究人员对纳米颗粒的绿色环保合成的关注。本研究报告了使用毛叶肉桂的叶子提取物绿色合成氧化铜纳米颗粒（CuO NPs）在适当的条件下。观察到叶提取物可以作为还原剂和稳定剂来合成CuO NP。合成的NP使用XRD表征。XRD图清楚地表明了合成组合物的晶体性质和单斜晶结构。使用Debye-Scherrer关系式计算平均晶体尺寸，发现为17nm。进行FT-IR分析是为了研究合成的CuO NP中存在的生物分子。用EDX确认CuO NPS的存在。TEM和SEM图像显示了NP的球形，计算出的NP的尺寸与XRD结果一致。测试了这些NP对四种人类致病菌的革兰氏阳性（S.aureus）和革兰氏阴性的抗菌活性（大肠杆菌，绿脓杆菌和奇异毕赤酵母）。合成的CuO NPs对所有四种细菌均显示出显着的抗菌活性。