The globus pallidus internus and the subthalamic nucleus are common targets for deep brain stimulation to alleviate symptoms of Parkinson's disease and dystonia. In the rodent models, however, their direct targeting is hindered by the relatively large dimensions of applied electrodes. To reduce the neurological damage, the electrodes are usually implanted cranial to the nuclei, thus exposing the non-targeted brain regions to large electric fields and, in turn, possible undesired stimulation effects. In this numerical study, we analyze the spread of the fields for the conventional electrodes and several modifications. As a result, we present a relatively simple electrode design that allows an efficient focalization of the stimulating field in the inferiorly located nuclei.

苍白球内侧和丘脑下核是深部脑刺激以减轻帕金森氏病和肌张力障碍症状的常见靶标。然而，在啮齿动物模型中，所施加电极的相对较大尺寸阻碍了它们的直接靶向。为了减少神经损伤，通常将电极颅骨植入到核中，从而将非目标大脑区域暴露于大电场中，进而可能产生不希望的刺激效果。在此数值研究中，我们分析了常规电极的电场分布和几种改进。结果，我们提出了一种相对简单的电极设计，该电极设计可以有效地聚焦位于下方原子核中的刺激场。