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Quality of systematic reviews in HIV: The case of clinical outcomes associated with patient medication adherence
Journal of Evidence-Based Medicine ( IF 7.3 ) Pub Date : 2021-02-02 , DOI: 10.1111/jebm.12423
Joanita Lake 1, 2 , Kendra A Lawrence 1 , Elena Martinez Alonso 1 , Valerie Gonzales 1 , Joanne LaFleur 1, 2
Affiliation  

Use of systematic reviews (SRs) as first‐level evidence for guideline recommendations hinges on review quality. In particular, US guidelines for adherence‐related recommendations in the treatment of human immunodeficiency virus (HIV) are not based on available SRs of adherence‐outcome relationships; it is unclear why. No published studies report on the quality of SRs on HIV adherence and outcomes, which may be driving the lack of use. We describe the quality of this body of literature.

中文翻译:

HIV 系统评价的质量:与患者服药依从性相关的临床结果案例

使用系统评价 (SR) 作为指南推荐的一级证据取决于评价质量。特别是,美国关于治疗人类免疫缺陷病毒 (HIV) 依从性相关建议的指南不是基于现有的依从性-结果关系的 SR;目前还不清楚为什么。没有发表的研究报告关于 HIV 依从性和结果的 SR 的质量,这可能是导致使用不足的原因。我们描述了这组文献的质量。
更新日期:2021-02-26
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