Infant skin is highly absorptive and sensitive to exposure from external agents (microbes, toxicants, heat, cold, etc.). Many specialized infant skincare products are currently commercially available. Although the manufacturers claim that their products are mild enough to suit the infant skin, these products need to be studied for their safety. Using animal models to examine the safety of the ever-increasing number of skincare products is not economically or logistically feasible. To overcome this problem, we suggest using a battery of microbial bioassays as a robust system for monitoring the mutagenic potential of skincare products. We picked popular infant skincare products from the Indian market and assessed them by using a battery of three microbial mutagenicity bioassays. Most of them showed significant and reproducible mutagenic potential. Our study results raise concerns about regular use of infant products and emphasize the need to enforce strict regulations for the manufacturing and safety assessment of infant products.

婴儿皮肤具有高度吸收性，并且对外界因素（微生物，毒物，热，冷等）的暴露敏感。当前，许多专门的婴儿护肤产品是可商购的。尽管制造商声称其产品足够温和以适合婴儿皮肤，但仍需要对这些产品进行安全性研究。使用动物模型来检查越来越多的护肤产品的安全性在经济或物流上都不可行。为了克服这个问题，我们建议使用一系列微生物生物测定作为监测护肤产品诱变潜力的强大系统。我们从印度市场上挑选了流行的婴儿护肤产品，并通过一系列的三种微生物诱变生物测定法对其进行了评估。它们中的大多数显示出显着且可再现的诱变潜力。