Antibiotic contamination of the water environment has attracted much attention from researchers because of their potential hazards to humans and ecosystems. In this study, a multi-template molecularly imprinted polymer (MIP) modified mesoporous silica coated magnetic graphene oxide (MGO@MS@MIP) was prepared by the surface imprinting method via a sol-gel process and was used for the selective, efficient and simultaneous removal of tetracyclines (TCs), including doxycycline (DC), tetracycline (TC), chlorotetracycline (CTC) and oxytetracycline (OTC) from water. The synthesized MIP composite was characterized by Fourier transform infrared spectroscopy, transmission electron microscope and thermogravimetric analysis. The adsorption properties of MGO@MS@MIP for these TCs were characterized through adsorption kinetics, isotherms and selectivity tests. The MIP composite revealed larger adsorption quantities, excellent selectivity and rapid kinetics for these four tetracyclines. The adsorption process was spontaneous and endothermic and followed the Freundlich isotherm model and the pseudo-second-order kinetic model. The MGO@MS@MIP could specifically recognize DC, TC, CTC and OTC in the presence of some chemical analogs. In addition, the sorption capacity of the MIP composite did not decrease significantly after repeated application for at least five cycles. Thus, the prepared magnetic MIP composite has great potential to contribute to the effective separation and removal of tetracyclines from water.

水环境中的抗生素污染因其对人类和生态系统的潜在危害而引起了研究人员的广泛关注。在这项研究中，通过表面印迹法通过溶胶-凝胶法制备了多模板分子印迹聚合物（MIP）改性的介孔二氧化硅涂层磁性氧化石墨烯（MGO @ MS @ MIP），该方法用于选择性，高效和高效同时从水中去除四环素（TC），包括强力霉素（DC），四环素（TC），氯四环素（CTC）和土霉素。通过傅立叶变换红外光谱，透射电镜和热重分析对合成的MIP复合材料进行了表征。通过吸附动力学，等温线和选择性试验表征了MGO @ MS @ MIP对这些TC的吸附性能。MIP复合材料对这四个四环素显示出更大的吸附量，优异的选择性和快速的动力学。吸附过程是自发的且是吸热的，遵循弗氏等温线模型和拟二级动力学模型。MGO @ MS @ MIP可以在存在某些化学类似物的情况下专门识别DC，TC，CTC和OTC。另外，在重复施加至少五个循环之后，MIP复合材料的吸附能力没有显着降低。因此，制备的磁性MIP复合材料具有很大的潜力，有助于有效地从水中分离和去除四环素。吸附过程是自发的且是吸热的，遵循弗氏等温线模型和拟二级动力学模型。MGO @ MS @ MIP可以在存在某些化学类似物的情况下专门识别DC，TC，CTC和OTC。另外，在重复施加至少五个循环之后，MIP复合材料的吸附能力没有显着降低。因此，制备的磁性MIP复合材料具有很大的潜力，有助于有效地从水中分离和去除四环素。吸附过程是自发的且是吸热的，遵循弗氏等温线模型和拟二级动力学模型。MGO @ MS @ MIP可以在存在某些化学类似物的情况下专门识别DC，TC，CTC和OTC。另外，在重复施加至少五个循环之后，MIP复合材料的吸附能力没有显着降低。因此，制备的磁性MIP复合材料具有很大的潜力，有助于有效地从水中分离和去除四环素。