A commercially available small‐angle X‐ray scattering (SAXS) NanoSTAR instrument (Bruker AXS) with a liquid‐metal‐jet source (Excillum) has been optimized for solution scattering and installed at iNANO at Aarhus University. The instrument (named HyperSAXS) employs long high‐quality parabolic Montel multilayer optics (Incoatec) and a novel compact scatterless pinhole slit with Ge edges, which was designed and built at Aarhus University. The combination of the powerful source and optimized geometry gives an integrated X‐ray intensity close to 10⁹ photons s⁻¹ for a standard range of scattering vector moduli q = 0.0098–0.425 Å⁻¹, where q = (4πsingθ)/λ and λ is the Ga Kα wavelength of 1.34 Å. The high intensity of the instrument makes it possible to measure dilute samples of, for example, protein or surfactant with concentrations of 1 mg ml⁻¹ in a few minutes. A flow‐through cell, built at Aarhus University, in combination with an automated sample handler has been installed on the instrument. The sample handler is based on the commercial Gilson GX‐271 injection system (Biolab), which also allows samples to be stored under thermostatted conditions. The sample handler inserts and removes samples, and also cleans and dries the sample cell between measurements. The minimum volume of the flow‐through capillary is about 20 µl. The high intensity additionally allows time‐resolved measurements to be performed with a temporal resolution of seconds. For this purpose a stopped‐flow apparatus, (SFM‐3000, Bio‐Logic) was connected to the flow‐through cell by high‐performance liquid chromatography tubing. This configuration was chosen as it allows vacuum around the sample cell and thus maintains a low background. The instrument can readily be converted into a low‐q setup with a q range of 0.0049–0.34 Å⁻¹ and an X‐ray intensity of about 5 × 10⁷ photons s⁻¹.

中文翻译：

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高通量自动化实验室小角度X射线散射仪，针对溶液散射进行了优化

带有液体金属喷射源（Excillum）的市售小角度X射线散射（SAXS）NanoSTAR仪器（Bruker AXS）已针对溶液散射进行了优化，并安装在奥胡斯大学的iNANO上。该仪器（名称为HyperSAXS）采用了高质量的抛物线型Montel多层光学器件（Incoatec）和新颖的带有Ge边缘的紧凑型无散射针孔狭缝，由奥胡斯大学设计和制造。强大的源的组合和优化的几何形状给出了一个集成的X射线的强度接近10个⁹ 光子小号^-1为一个标准范围散射矢量模量q = 0.0098-0.425埃^-1，其中q =（4πsingθ）/λ和λ是Ga  Kα波长为1.34Å。仪器的高强度使得可以测量浓度为1 mg ml ^-1的稀薄样品，例如蛋白质或表面活性剂在几分钟内。仪器上已安装了由奥尔胡斯大学（Aarhus University）建造的流通池以及自动样品处理机。样品处理器基于商业的Gilson GX-271进样系统（Biolab），该系统还允许将样品存储在恒温条件下。样品处理器可以插入和取出样品，还可以在两次测量之间清洗和干燥样品池。流通毛细管的最小容积约为20 µl。高强度还允许以秒为单位的时间分辨率执行时间分辨的测量。为此，通过高效液相色谱管将停流设备（SFM-3000，Bio-Logic）连接到流通池。选择此配置是因为它允许样品池周围保持真空，从而保持较低的背景。仪器可以很容易地转换为低q的设置，q范围为0.0049–0.34Å ^-1，X射线强度约为5×10 ⁷ 光子s ^-1。