During his fifty-five year tenure, Prof. Barry M. Trost has made countless advancements in the fields of synthetic method development and complex molecule total synthesis. In addition to his well-known contributions in the areas of allylic alkylation and transition metal-catalyzed cycloisomerization reactions, Prof. Trost has developed many other useful synthetic methods as well. Although less prominent than some of his hallmark transformations, these reactions are no less significant and have enjoyed widespread adoption by the synthetic community. This review highlights many of these unsung processes – including several reduction/oxidation reactions, metal-catalyzed alkene-alkyne and alkyne-alkyne couplings, phosphine-catalyzed redox isomerizations, and methods for determining absolute stereochemistry – and their utility in the total synthesis of natural products, pharmaceuticals, and other complex bioactive molecules.

中文翻译：

---

超越烯丙基烷基化：Trost 化学在复杂分子合成中的应用

在他 55 年的任期内，Barry M. Trost 教授在合成方法开发和复杂分子全合成领域取得了无数进步。除了他在烯丙基烷基化和过渡金属催化的环异构化反应领域的著名贡献外，Trost 教授还开发了许多其他有用的合成方法。虽然不如他的一些标志性转变突出，但这些反应同样重要，并已被合成社区广泛采用。这篇综述重点介绍了许多这些鲜为人知的过程——包括几种还原/氧化反应、金属催化的烯烃-炔烃和炔烃-炔烃偶联、膦催化的氧化还原异构化、