The development of electrocatalysts for the oxygen reduction reaction (ORR) with high activity and cost-effectiveness is indispensable for sustainable energy storage and conversion technologies. Featured with maximum atomic efficiency and well-defined structure characteristics, carbon-based single-atomic site (SAS) catalysts are regarded as the most potential next-generation ORR catalysts. Despite the substantial efforts on the study of SAS catalysts, there still exists a large gap between them and platinum group metal (PGM) catalysts in the performance. Particularly, the unique metal-support interactions are believed to alter the charge state of the SAS by electron transfer between SAS and the support, resulting in the activated reactants and enhanced catalytic process of SAS catalysts. Inspired by this, the addition of some synergistic components is desirable to accurately tune the interactions and endow the SAS with the optional local environment, leading to improved performance. In this review, we provide a comprehensive overview of recent advances in synergistically enhanced SAS for boosted ORR. First, ORR mechanism and description of SAS catalysts towards ORR are provided. Then, a variety of novel synthetic strategies and advanced characterization techniques for SAS catalysts are briefly introduced. Emphatically, several synergistic components for SAS were systematically summarized. Finally, the current challenges and perspectives are proposed for the future development of SAS catalysts towards ORR.

具有高活性和成本效益的用于氧还原反应（ORR）的电催化剂的开发对于可持续的能量存储和转化技术必不可少。碳基单原子中心（SAS）催化剂具有最大的原子效率和明确的结构特征，被认为是最有潜力的下一代ORR催化剂。尽管在研究SAS催化剂方面付出了巨大的努力，但它们与铂族金属（PGM）催化剂之间在性能上仍然存在很大差距。特别地，据信独特的金属-载体相互作用通过SAS与载体之间的电子转移来改变SAS的电荷状态，从而导致活化的反应物和SAS催化剂的增强的催化过程。受此启发，需要添加一些协同组件来准确地调整交互并使SAS具有可选的本地环境，从而提高性能。在这篇评论中，我们提供了协同增强的SAS用于增强ORR的最新进展的全面概述。首先，提供了ORR机理和SAS催化剂对ORR的描述。然后，简要介绍了SAS催化剂的各种新颖合成策略和先进的表征技术。着重指出了SAS的几个协同组件。最后，针对SAS催化剂向ORR的未来发展提出了当前的挑战和观点。在这篇评论中，我们提供了协同增强的SAS用于增强ORR的最新进展的全面概述。首先，提供了ORR机理和SAS催化剂对ORR的描述。然后，简要介绍了SAS催化剂的各种新颖合成策略和先进的表征技术。着重指出了SAS的几个协同组件。最后，针对SAS催化剂向ORR的未来发展提出了当前的挑战和观点。在这篇评论中，我们提供了协同增强的SAS用于增强ORR的最新进展的全面概述。首先，提供了ORR机理和SAS催化剂对ORR的描述。然后，简要介绍了SAS催化剂的各种新颖合成策略和先进的表征技术。着重指出了SAS的几个协同组件。最后，针对SAS催化剂向ORR的未来发展提出了当前的挑战和观点。着重指出了SAS的几个协同组件。最后，针对SAS催化剂向ORR的未来发展提出了当前的挑战和观点。着重指出了SAS的几个协同组件。最后，针对SAS催化剂向ORR的未来发展提出了当前的挑战和观点。