The issue of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has created enormous threat to global health. In an effort to contain the spread of COVID-19, a huge amount of disinfectants and antibiotics have been utilized on public health. Accordingly, the concentration of disinfectants and antibiotics is increasing rapidly in various environments, including wastewater, surface waters, soils and sediments. The aims of this study were to analyze the potential ecological environment impacts of disinfectants and antibiotics by summarizing their utilization, environmental occurrence, distribution and toxicity. The paper highlights the promoting effects of disinfectants and antibiotics on antibiotic resistance genes (ARGs) and even antibiotic resistant bacteria (ARB). The scientific evidences indicate that the high concentration and high dose of disinfectants and antibiotics promote the evolution toward antimicrobial resistance through horizontal gene transformation and vertical gene transformation, which threaten human health. Further concerns should be focused more on the enrichment, bioaccumulation and biomagnification of disinfectants, antibiotics, antibiotic resistance genes (ARGs) and even antibiotic resistant bacteria (ARB) in human bodies.

由严重急性呼吸系统综合症冠状病毒2（SARS-CoV-2）引起的冠状病毒疾病2019（COVID-19）问题对全球健康构成了巨大威胁。为了控制COVID-19的传播，已在公共卫生中使用了大量的消毒剂和抗生素。因此，在包括废水，地表水，土壤和沉积物在内的各种环境中，消毒剂和抗生素的浓度正在迅速增加。这项研究的目的是通过总结消毒剂和抗生素的利用，环境发生，分布和毒性来分析其对生态环境的潜在影响。该论文重点介绍了消毒剂和抗生素对抗生素抗性基因（ARG）甚至抗生素抗性细菌（ARB）的促进作用。科学证据表明，高浓度和高剂量的消毒剂和抗生素可通过水平基因转化和垂直基因转化促进对抗菌素耐药性的演变，从而威胁到人类健康。进一步的关注应更多地集中在人体中消毒剂，抗生素，抗生素抗性基因（ARG）甚至抗生素抗性细菌（ARB）的富集，生物富集和生物放大。