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DBU-Catalyzed Highly Efficient Synthesis of 1,4-Dihydropyridine Derivatives from Arylidenemalononitriles and
Heterocycles ( IF 0.6 ) Pub Date : 2021-01-28 , DOI: 10.3987/com-20-14382
Takeshi Oriyama , Wei Han , Kazuya Nakajima , Masashi Kajitani

Various 1,4-dihydropyridine derivatives were efficiently synthesized from arylidenemalononitriles and β-enamino imides using DBU (3 mol%) as the catalyst at room temperature. This mild, straightforward high-yielding protocol was atom-economy, time-economy, with a low catalyst load, and without the need for reflux.

中文翻译:

DBU催化从丙烯叉基丙二腈和丙烯腈高效合成1,4-二氢吡啶衍生物

在室温下,使用DBU(3 mol%)作为催化剂,芳基丙二腈β-烯氨基酰亚胺有效地合成了各种1,4-二氢吡啶衍生物。这种温和,简单,高产的方案是原子经济,时间经济,催化剂负载低且无需回流。
更新日期:2021-04-01
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