Objective. Asthma and sleep-related breathing disorders (SRBD) are common chronic respiratory diseases in children. The relationship between asthma and SRDB is bidirectional. However, only a few studies have analyzed the relationship between asthma control status and risk of SRBD. The aim of this study was to evaluate the relationship between asthma control and SRBD and further assess the relationship between therapy/atopy/lung function of children with asthma and SRBD. Methods. A total of 209 children aged 3–16 years were enrolled in this study. Pediatric sleep questionnaire (PSQ) scores were used to identify children at high risk of developing SRBD. Data on asthma control status, therapy, allergy, lung function, and exhaled nitric oxide were collected. Results. A significantly higher risk of SRBD was found among children with poorly controlled asthma (34.25% vs. 13.97%,  < 0.01) and allergic rhinitis (AR) (34.29% vs. 13.92%,  < 0.01) than among children with well-controlled asthma and AR. The prevalence of SRBD was also significantly higher in asthmatic children with obesity than that with just obesity (42.11% vs. 20.00%,  < 0.05). Multiple logistic regression analysis showed that poorly controlled asthma (OR, 2.746 (95% CI, 1.215–6.209);  < 0.05) and poorly controlled AR (OR, 3.284 (95% CI, 1.430–7.544);  < 0.01) increased the odds of having SRBD. Conclusion. Poorly controlled asthma and AR increase the risk of SRBD. A routine check of the level of asthma control and appropriate use of medication for AR are important because of their influence on SRBD.

中文翻译：

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哮喘儿童哮喘控制不良与睡眠相关呼吸障碍之间的关系：一项两中心研究

客观的。哮喘和睡眠相关呼吸障碍（SRBD）是儿童常见的慢性呼吸系统疾病。哮喘和 SRDB 之间的关系是双向的。然而，只有少数研究分析了哮喘控制状态与 SRBD 风险之间的关系。本研究的目的是评估哮喘控制与 SRBD 之间的关系，并进一步评估哮喘儿童的治疗/特应性/肺功能与 SRBD 之间的关系。方法。共有 209 名 3-16 岁的儿童参与了这项研究。儿科睡眠问卷 (PSQ) 评分用于识别发生 SRBD 的高风险儿童。收集有关哮喘控制状态、治疗、过敏、肺功能和呼出一氧化氮的数据。结果。 哮喘控制不佳的儿童（34.25% vs. 13.97%， < 0.01）和过敏性鼻炎（AR）（34.29% vs. 13.92%， < 0.01）的 SRBD 风险显着高于 哮喘控制良好的儿童。和增强现实。肥胖哮喘儿童的 SRBD 患病率也显着高于单纯肥胖儿童（42.11% vs. 20.00%， < 0.05）。多元逻辑回归分析显示，哮喘控制不佳（OR，2.746（95% CI，1.215–6.209）； < 0.05）和 AR 控制不佳（OR，3.284（95% CI，1.430–7.544）； < 0.01）增加了患病几率拥有 SRBD。结论。哮喘和 AR 控制不佳会增加 SRBD 的风险。哮喘控制水平的常规检查和 AR 药物的适当使用非常重要，因为它们对 SRBD 具有影响。