当前位置: X-MOL 学术Res. Microbiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Involvement of amyloid proteins in the formation of biofilms in the pathogenic yeast Candida albicans
Research in Microbiology ( IF 2.6 ) Pub Date : 2021-01-28 , DOI: 10.1016/j.resmic.2021.103813
Thierry Mourer 1 , Mennat El Ghalid 1 , Christophe d'Enfert 1 , Sophie Bachellier-Bassi 1
Affiliation  

Candida species represent a major fungal threat for human health. Within the Candida genus, the yeast Candida albicans is the most frequently incriminated species during episodes of candidiasis or candidemia. Biofilm formation is used by C. albicans to produce a microbial community that is important in an infectious context. The cell wall, the most superficial cellular compartment, is of paramount importance regarding the establishment of biofilms. C. albicans cell wall contains proteins with amyloid properties that are necessary for biofilm formation due to their adhesion properties. This review focuses on these amyloid proteins during biofilm formation in the yeast C. albicans.



中文翻译:

淀粉样蛋白参与致病酵母白色念珠菌生物膜的形成

念珠菌是对人类健康的主要真菌威胁。在念珠菌属中,酵母白色念珠菌是念珠菌病或念珠菌血症发作期间最常被感染的物种。白色念珠菌利用生物膜形成来产生在感染环境中很重要的微生物群落。细胞壁是最表面的细胞隔室,对于生物膜的建立至关重要。白色念珠菌细胞壁含有具有淀粉样蛋白特性的蛋白质,由于它们的粘附特性,这些蛋白质是生物膜形成所必需的。本综述重点关注酵母白色念珠菌生物膜形成过程中的这些淀粉样蛋白。

更新日期:2021-01-28
down
wechat
bug