This work reports on the covalent linkage of (3-aminopropyl)triethoxysilane (APTES) functionalised iron oxide (IONPs–APTES) and silica (SiNPs–APTES) nanoparticles with zinc(II) tetra–([3–(4–phenoxy) propanoic acid) phthalocyanine] (1) and zinc(II) mono–([3–(4–phenoxy) propanoic acid) phthalocyanine (2) via an amide bond to form the conjugates, 1–IONPs-APTES, 1–SiNPs–APTES, 2-IONPs-APTES and 2-SiNPs-APTES). The photophysicochemical behaviour of the conjugates was investigated. These were characterized by a decrease in the fluorescence quantum yields and lifetimes, and an increase in the triplet quantum yield and singlet oxygen quantum yield when compared to complex 1 and 2 alone. The conjugates to IONPs-APTES displayed higher Φ_T than those of SiNPs-APTES probably due to the heavy atom effect of iron compared to silica and the high loading capacity of the relatively smaller iron oxide NPs, however, there was no significant difference in the Φ_Δ values of 2-IONPs-APTES (Φ_Δ=0.59) and 2-SiNPs-APTES (Φ_Δ=0.58), suggesting that the energy transfer process between the excited triplet state of 2-IONPs-APTES and ground state molecular oxygen was not effective. Photodynamic antimicrobial chemotherapy (PACT) studies showed that linkage of Pcs to NPs improves their photoinactivation capability against Staphylococcus aureus and Escherichia coli. IONPs-APTES and its conjugates generally displayed the highest log reductions than SiNPs-APTES and its conjugates except for studies after 75 min of irradiation for S. Aureus where the log reductions are the same. 2-IONP-APTES was recovered using a magnet after each photodegradation cycle and its stability after 3 cycles confirmed re-usability.

这项工作报告了（3-氨基丙基）三乙氧基硅烷（APTES）官能化的氧化铁（IONPs-APTES）和二氧化硅（SiNPs-APTES）纳米粒子与锌（II）四-（[3-（4-苯氧基）]丙酸的共价连接酸]酞菁]（1）和锌（II）单-（[3-（4-苯氧基）丙酸）酞菁锌（2）通过酰胺键形成共轭物，1 -IONPs-APTES，1 -SiNPs-APTES ，2 -IONPs-APTES和2 -SiNPs-APTES）。研究了缀合物的光物理化学行为。与络合物1相比，其特征在于荧光量子产率和寿命降低，三重态量子产率和单重态氧量子产率提高。和2个。到IONPs-APTES缀合物显示高Φ _Ť比那些可能SiNPs-APTES由于与二氧化硅和相对较小的氧化铁纳米颗粒的高负载能力的铁的重原子效应，然而，有一个在无显著差异Φ _Δ的值2 -IONPs-APTES（Φ _Δ= 0.59）和2个-SiNPs-APTES（Φ _Δ= 0.58），这表明的激发三重态之间的能量转移过程2 -IONPs-APTES和基态分子氧没有效果。光动力抗微生物化学疗法（PACT）研究表明，Pcs与NPs的连接可改善其对PNP的光灭活能力金黄色葡萄球菌和大肠杆菌。IONPs-APTES及其偶联物通常表现出最高的对数减少比SiNPs-APTES和其结合物除了后照射75分钟研究金黄色葡萄球菌，其中的对数减少是相同的。在每个光降解循环后，使用磁铁回收2 -IONP-APTES，并且在3个循环后的稳定性证实了可重复使用性。