Chiral ligand conjugated transition metal oxide nanoparticles (NPs) are a promising platform for chiral recognition, biochemical sensing, and chiroptics. Herein, we present chirality-based strategy for effective sensing of mercury ions via ligand-induced chirality derived from metal-to-ligand charge transfer (MLCT) effects. The ligand competition effect between molybdenum and heavy metal ions such as mercury is designated to be essential for MLCT chirality. With this know-how, mercury ions, which have a larger stability constant ($K_f$) than molybdenum, can be selectively identified and quantified with a limit of detection (LOD) of 0.08 and 0.12 nmol/L for D-cysteine and L-cysteine (Cys) capped ${\mathrm{MoO}}_2$ NPs. Such chiral chemical sensing nanosystems would be an ideal prototype for biochemical sensing with a significant impact on the field of biosensing, biological systems, and water research-based nanotoxicology.

中文翻译：

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基于金属到配体电荷转移手性的汞离子感测

手性配体共轭过渡金属氧化物纳米粒子（NPs）是用于手性识别，生化传感和按摩疗法的有前途的平台。在本文中，我们介绍了基于手性的策略，可通过金属到配体的电荷转移（MLCT）效应，通过配体诱导的手性有效感测汞离子。钼和重金属离子（例如汞）之间的配体竞争效应被指定为MLCT手性必不可少的。有了这种专业知识，汞离子的稳定性常数就更大了（${ķ}_F$）相对于钼，可以选择性地鉴定和定量，D-半胱氨酸和L-半胱氨酸（Cys）的检出限（LOD）为0.08和0.12 nmol / L $O_2$NP。这种手性化学传感纳米系统将是生物化学传感的理想原型，对生物传感，生物系统和基于水研究的纳米毒理学领域产生重大影响。