Relationships between iron-dependent ferroptosis and nerve system diseases have been recently revealed. However, the role of ferroptosis in neuropathic pain (NeP) remains to be elucidated. Thus, we aimed to investigate whether ferroptosis in spinal cord contributes to NeP induced by a chronic constriction injury (CCI) of the sciatic nerve.

中文翻译：

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抑制铁死亡样细胞死亡减轻大鼠周围神经损伤引起的神经性疼痛反应

最近揭示了铁依赖性铁死亡与神经系统疾病之间的关系。然而，铁死亡在神经性疼痛 (NeP) 中的作用仍有待阐明。因此，我们旨在研究脊髓中的铁死亡是否会导致坐骨神经慢性收缩损伤 (CCI) 诱导的 NeP。