The paper by Malek Mansour and Garcia [Phys. Rev. E 101, 052135 (2020)] is shown to be based on misconceptions in the stochastic formulation of chemical thermodynamics in reactive systems. Their erroneous claims, asserting that entropy production cannot be correctly evaluated using path probabilities whenever the reactive system involves more than one elementary reaction leading to the same composition changes, are refuted.

中文翻译：

---

评论“反应系统中路径热力学的有效性”

Malek Mansour和Garcia的论文[ Phys。启ë 101，052135（2020）]被显示为基于在反应体系化学热力学随机制剂误解。他们的错误主张被驳斥，他们断言每当反应体系涉及导致同一组成变化的一个以上基本反应时，就不能使用路径概率来正确评估熵的产生。