A 10-month-old mixed-breed male dog was presented with an oblique tibial fracture. The dog was treated with a Robert Jones-like bandage as a conservative approach, and was subjected to X-ray, B-mode, Color Doppler and contrast-enhanced ultrasound (CEUS) examinations during the fracture healing, in order to assess bone hemodynamic changes. B-mode, Power Doppler and CEUS examinations of the fracture gap were performed at 7, 20, 35, and 50 days post-trauma. Quantitative analysis of CEUS and perfusion parameters were obtained. On CEUS, a steep incline in signal numbers was visible in fracture gap at 7 days with peaks at 35 days, after which the vascularization decreases gradually over the next days. In this study, CEUS provided important information on the early stages of the callus formation and on the healing of neighboring tissues, allowing recognition of a correct bone healing. Moreover, the number of vascular signals on CEUS was greater than that on Doppler images on the same day. This report showed the application of CEUS in controlling the fracture healing process. CEUS could be a method of monitoring the remedial processes, assessing the tibial fracture perfusion characterized by low-velocity, small-volume blood flows.

中文翻译：

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对比超声在非手术治疗小狗胫骨骨折中的骨愈合评价

一只10个月大的杂种公狗出现了胫骨斜位骨折。这只狗用罗伯特·琼斯（Robert Jones）式绷带作为保守治疗方法，在骨折愈合期间接受了X射线，B型，彩色多普勒和造影剂超声（CEUS）检查，以评估骨的血流动力学变化。在创伤后第7、20、35和50天对骨折间隙进行B型，Power Doppler和CEUS检查。对CEUS和灌注参数进行了定量分析。在CEUS上，在第7天的骨折间隙中可见明显的信号编号倾斜，在第35天达到峰值，此后在接下来的几天中血管生成逐渐减少。在这项研究中，CEUS提供了有关愈伤组织形成早期以及邻近组织愈合的重要信息，可以识别正确的骨愈合。此外，CEUS上的血管信号数量要多于同一天的多普勒图像。该报告显示了CEUS在控制骨折愈合过程中的应用。CEUS可能是一种监测补救过程，评估以低速，小流量血流为特征的胫骨骨折灌注的方法。