Cell wall integrity control in plants involves multiple signaling modules that are mostly defined by genetic interactions. The putative co-receptors FEI1 and FEI2 and the extracellular glycoprotein FLA4 present the core components of a signaling pathway that acts in response to environmental conditions and insults to cell wall structure to modulate the balance of various growth regulators and, ultimately, to regulate the performance of the primary cell wall. Although the previously established genetic interactions are presently not matched by intermolecular binding studies, numerous receptor-like molecules that were identified in genome-wide interaction studies potentially contribute to the signaling machinery around the FLA4-FEI core. Apart from its function throughout the model plant Arabidopsis thaliana for the homeostasis of growth and stress responses, the FLA4-FEI pathway might support important agronomic traits in crop plants.

中文翻译：

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FLA4-FEI途径：与细胞壁结构和应激信号传导有关的独特而神秘的信号传导模块

植物中细胞壁完整性的控制涉及多个信号传导模块，这些模块主要由遗传相互作用定义。推定的共受体FEI1和FEI2以及细胞外糖蛋白FLA4代表信号通路的核心成分，该信号通路响应环境条件而起作用，并损害细胞壁结构，以调节各种生长调节剂的平衡，并最终调节其性能。原代细胞壁。尽管目前尚未通过分子间结合研究来确定先前建立的遗传相互作用，但在全基因组相互作用研究中鉴定出的许多受体样分子可能会促进FLA4-FEI核心周围的信号传导机制。除了在整个模型植物拟南芥中的功能外 对于生长和胁迫响应的稳态，FLA4-FEI途径可能支持农作物的重要农艺性状。