Incorporating antibacterial agent into biomimetic coating inspired by natural organisms with micro-nano structure surface has generated more interest for antifouling applications. In this work, poly(dimethylsiloxane) (PDMS)-based triblock copolymers and sub-20 nm nanoparticles Ag and heterogeneous Fe₃O₄-coated Ag (Fe₃O₄@Ag) were used to construct microphase separation topography with oriented copolymer blocks structure. The artificial surface was verified by atomic force microscopy and scanning electron microscopy images. Meanwhile, the surface exhibited relative stable hydrophobic property, which was demonstrated by the water contact angle and dynamic air-bubble contact angle measurements. Consequently, after immersed in BSA solution 24 h and 720 h, the actual BSA absorption amount of the surface with Fe₃O₄@Ag nanoparticles was as low as 10% and 27% that of the initial BSA amount, respectively. Moreover, the surface also showed remarkable antibacterial performance, which effectively suppressed the growth rate of Escherichia coli. The strategy of constructing the flexible microphase separation structure by introducing heterogeneous inorganic antibacterial nanoparticles into a block copolymer substrate opens up a new way to create an antifouling surface coating.

在具有微纳米结构表面的自然生物的启发下，将抗菌剂掺入仿生涂料中引起了人们对于防污应用的更多兴趣。在这项工作中，基于聚二甲基硅氧烷（PDMS）的三嵌段共聚物和20 nm以下的纳米粒子Ag和非均质的Fe ₃ O ₄涂层的Ag（Fe ₃ O ₄（Ag）用于构建具有定向共聚物嵌段结构的微相分离形貌。通过原子力显微镜和扫描电子显微镜图像验证了人造表面。同时，表面表现出相对稳定的疏水性，这通过水接触角和动态气泡接触角测量得到证明。因此，浸入BSA溶液24小时和720小时后，Fe ₃ O ₄ @Ag纳米粒子在表面的实际BSA吸收量分别低至初始BSA量的10％和27％。而且，表面还表现出显着的抗菌性能，有效抑制了大肠杆菌的生长速度。通过将异质无机抗菌纳米粒子引入嵌段共聚物基材中来构建柔性微相分离结构的策略，开辟了一种新的方法来创建防污表面涂层。