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Triterpenoids from Walsura trichostemon
Journal of Natural Medicines ( IF 3.3 ) Pub Date : 2021-01-22 , DOI: 10.1007/s11418-021-01483-4 Alfarius Eko Nugroho , Yusuke Hirasawa , Toshio Kaneda , Osamu Shirota , Michiyo Matsuno , Hajime Mizukami , Hiroshi Morita
中文翻译:
Walsura trichostemon的三萜
更新日期:2021-01-22
Journal of Natural Medicines ( IF 3.3 ) Pub Date : 2021-01-22 , DOI: 10.1007/s11418-021-01483-4 Alfarius Eko Nugroho , Yusuke Hirasawa , Toshio Kaneda , Osamu Shirota , Michiyo Matsuno , Hajime Mizukami , Hiroshi Morita
Bioactivity guided separation of Walsura trichostemon stem methanolic extract led to the isolation of four new dammarane (1–4) and two new apotirucallane triterpenoids (5–6), together with one limonoid (7), 11,25-dideacetyltrichostemonate, 12β, 20S, 24R-trihydroxydammar-25-en-3-one and 12β, 20S, 25-trihydroxydammar-23-en-3-one. Compounds 1–7 showed in vitro inhibitory activity on the proliferation of A549, human lung adenocarcinoma cell line.
中文翻译:
Walsura trichostemon的三萜
生物活性引导的分离割舌树属trichostemon干导致的四个新的达玛烷(隔离甲醇提取物1 - 4)和两个新的三萜类化合物apotirucallane(5 - 6与一个柠檬苦素(一起)7),11,25-dideacetyltrichostemonate,12β,20 S,24 R-三羟基达玛-25-en-3-one和12β,20 S,25-三羟基达玛-23-en-3-one。化合物1 – 7对人肺腺癌细胞系A549的增殖具有体外抑制活性。