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Fe-S Protein Synthesis in Green Algae Mitochondria
Plants ( IF 4.658 ) Pub Date : 2021-01-21 , DOI: 10.3390/plants10020200
Diego F. Gomez-Casati , Maria V. Busi , Julieta Barchiesi , Maria A. Pagani , Noelia S. Marchetti-Acosta , Agustina Terenzi

Iron and sulfur are two essential elements for all organisms. These elements form the Fe-S clusters that are present as cofactors in numerous proteins and protein complexes related to key processes in cells, such as respiration and photosynthesis, and participate in numerous enzymatic reactions. In photosynthetic organisms, the ISC and SUF Fe-S cluster synthesis pathways are located in organelles, mitochondria, and chloroplasts, respectively. There is also a third biosynthetic machinery in the cytosol (CIA) that is dependent on the mitochondria for its function. The genes and proteins that participate in these assembly pathways have been described mainly in bacteria, yeasts, humans, and recently in higher plants. However, little is known about the proteins that participate in these processes in algae. This review work is mainly focused on releasing the information on the existence of genes and proteins of green algae (chlorophytes) that could participate in the assembly process of Fe-S groups, especially in the mitochondrial ISC and CIA pathways.

中文翻译:

绿藻线粒体中Fe-S蛋白的合成

铁和硫是所有生物的两个基本元素。这些元素形成Fe-S簇,它们作为辅因子存在于与细胞关键过程(如呼吸和光合作用)相关的多种蛋白质和蛋白质复合物中,并参与多种酶促反应。在光合生物中,ISC和SUF Fe-S簇的合成途径分别位于细胞器,线粒体和叶绿体中。胞质中还存在第三种生物合成机制,其功能依赖于线粒体。参与这些组装途径的基因和蛋白质主要在细菌,酵母,人类以及最近的高等植物中得到了描述。但是,对于参与藻类这些过程的蛋白质知之甚少。
更新日期:2021-01-21
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