Modular construction of multiple functionalized arenes from abundant feedstocks, stands as an unremitting pursue goal in synthetic chemistry, which would accelerate the discovery of new drugs an advanced materials. Herein, by using multiple C-H activation strategy, through judicious choice of versatile imidate ester as the key directing group, expedi-ent delivery of molecular libraries of densely functionalized sulfur-contained arenes. Further synthetic application was demonstrated by multiple C-H modification of fused arenes and pharmaceuticals such as Ibuprofen, and concise con-struction of biologically active molecules, Madam dihydrochloride and Bipenamol, was also achieved.

中文翻译：

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多重C–H激活使密集功能化含硫芳烃的模块化结构成为可能

从丰富的原料中模块化构建多种功能化的芳烃，是合成化学中不懈追求的目标，它将加速新药和先进材料的发现。本文中，通过使用多种CH活化策略，通过明智地选择通用的亚氨酸酯作为关键指导基团，可以方便地递送高官能度含硫芳烃的分子库。通过对稠合的芳烃和药物（如布洛芬）进行多次CH修饰，证明了其进一步的合成应用，并且还实现了对生物活性分子，二盐酸盐女士和双苯那莫尔的简明构建。