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The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support
Cancer Cell ( IF 50.3 ) Pub Date : 2021-01-21 , DOI: 10.1016/j.ccell.2021.01.004
Anja Irmisch 1 , Ximena Bonilla 2 , Stéphane Chevrier 3 , Kjong-Van Lehmann 2 , Franziska Singer 4 , Nora C Toussaint 4 , Cinzia Esposito 5 , Julien Mena 6 , Emanuela S Milani 7 , Ruben Casanova 3 , Daniel J Stekhoven 4 , Rebekka Wegmann 6 , Francis Jacob 8 , Bettina Sobottka 9 , Sandra Goetze 7 , Jack Kuipers 10 , Jacobo Sarabia Del Castillo 5 , Michael Prummer 4 , Mustafa A Tuncel 10 , Ulrike Menzel 11 , Andrea Jacobs 3 , Stefanie Engler 3 , Sujana Sivapatham 3 , Anja L Frei 9 , Gabriele Gut 5 , Joanna Ficek 2 , Nicola Miglino 12 , , Rudolf Aebersold 6 , Marina Bacac 13 , Niko Beerenwinkel 10 , Christian Beisel 11 , Bernd Bodenmiller 14 , Reinhard Dummer 1 , Viola Heinzelmann-Schwarz 15 , Viktor H Koelzer 9 , Markus G Manz 12 , Holger Moch 9 , Lucas Pelkmans 5 , Berend Snijder 16 , Alexandre P A Theocharides 12 , Markus Tolnay 17 , Andreas Wicki 18 , Bernd Wollscheid 7 , Gunnar Rätsch 19 , Mitchell P Levesque 1
Affiliation  

The application and integration of molecular profiling technologies create novel opportunities for personalized medicine. Here, we introduce the Tumor Profiler Study, an observational trial combining a prospective diagnostic approach to assess the relevance of in-depth tumor profiling to support clinical decision-making with an exploratory approach to improve the biological understanding of the disease.



中文翻译:

The Tumor Profiler Study:用于临床决策支持的集成、多组学、功能性肿瘤分析

分子分析技术的应用和整合为个性化医疗创造了新的机会。在这里,我们介绍了 Tumor Profiler 研究,这是一项观察性试验,结合了前瞻性诊断方法来评估深入肿瘤分析的相关性,以支持临床决策与探索性方法,以提高对疾病的生物学理解。

更新日期:2021-03-08
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