In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.

中文翻译：

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在二硫键连接的可溶性载体上合成完全保护的三核苷酸结构单元

近年来，制备完全保护的三核苷酸亚磷酰胺作为合成子用于基于密码子的基因文库合成以及从阻断剂中组装寡核苷酸受到了广泛关注。我们在这里描述了使用二硫化物接头在可溶性支持物上制备此类三核苷酸合成子。