Biofilm formation on biomaterials is a challenge in the health area. Antimicrobial substances based on nanomaterials have been proposed to solve this problem. The aim was to incorporate nanostructured silver vanadate decorated with silver nanoparticles (β-AgVO₃) into dental porcelains (IPS Inline and Ex-3 Noritake), at concentrations of 2.5% and 5%, and evaluate the surface characteristics (by SEM/EDS), antimicrobial activity (against Streptococcus mutans, Streptococcus sobrinus, Aggregatibacter actinomycetemcomitans, and Pseudomonas aeruginosa), silver (Ag⁺) and vanadium (V⁴⁺/V⁵⁺) ions release, and mechanical properties (microhardness, roughness, and fracture toughness). The β-AgVO₃ incorporation did not alter the porcelain’s components, reduced the S. mutans, S. sobrinus and A. actinomycetemcomitans viability, increased the fracture toughness of IPS Inline, the roughness for all groups, and did not affect the microhardness of the 5% group. Among all groups, IPS Inline 5% released more Ag⁺, and Ex-3 Noritake 2.5% released more V⁴⁺/V⁵⁺. It was concluded that the incorporation of β-AgVO₃ into dental porcelains promoted antimicrobial activity against S. mutans, S. sobrinus, and A. actinomycetemcomitans (preventing biofilm formation), caused a higher release of vanadium than silver ions, and an adequate mechanical behavior was observed. However, the incorporation of β-AgVO₃ did not reduce P. aeruginosa viability and increased the surface roughness of dental porcelains.

中文翻译：

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牙科瓷中杂化纳米材料的掺入：抗菌，化学和机械性能

在生物材料上形成生物膜是健康领域的一个挑战。已经提出了基于纳米材料的抗菌物质来解决这个问题。目的是将装饰有银纳米颗粒（β- AgVO ₃）的纳米结构钒酸银以2.5％和5％的浓度掺入牙科瓷器（IPS Inline和Ex-3 Noritake）中，并评估表面特性（通过SEM / EDS） ），抗菌活性（抗变形链球菌，表兄链球菌，Aggregatibacter放线杆菌，和铜绿假单胞菌），银（Ag ⁺）和钒（V ⁴⁺ / V ⁵⁺）离子的释放和机械性能（显微硬度，粗糙度和断裂韧性）。的β -AgVO ₃掺入不改变瓷的部件，减少了变形链球菌，远缘链球菌和A.放线活力，增加的IPS内联，粗糙度对于所有组的断裂韧性，并没有影响的显微硬度5％组。在所有组中，IPS Inline 5％释放出更多的Ag ⁺，而Ex-3 Noritake 2.5％释放出更多的V ⁴⁺ / V ⁵⁺。结论是，将β- AgVO ₃掺入牙科瓷器中可提高其对变形链球菌的抗菌活性。，S。sobrinus和A.放线菌（防止生物膜形成）引起的钒释放量高于银离子，并且观察到足够的机械行为。然而，掺入β- AgVO ₃不会降低铜绿假单胞菌的生存能力并不会增加牙科瓷器的表面粗糙度。