Abstract

Background

The prevalence and associated factors related to psychotic symptoms in older adults are understudied. The objectives were to assess the prevalence, incidence and factors associated with psychotic symptoms in a representative Greek sample of community living older adults.

Methods

The sample includes n = 1,904 residents of the cities of Larissa and Maroussi in Greece participating in the Hellenic Longitudinal Investigation of Aging and Diet study with available data at baseline and n = 947 individuals at the 3-year follow-up. Past-month presence of delusions and hallucinations was assessed on the grounds of the 17 symptoms of the Columbia University Scale for Psychopathology in Alzheimer's Disease and 14 symptoms of the Neuropsychiatric Inventory Questionnaire. A comprehensive neuropsychological assessment for probable diagnosis of dementia and physical comorbidity was carried out by neurologists. Penalized logistic regression analyses were used to assess the socio-economic and clinical factors associated with psychotic symptoms.

Results

Past-month prevalence of psychotic symptoms was 1.9% and 1.0% when excluding cases of dementia. The prevalence of any delusion and hallucination was 0.8% and 0.3% when excluding dementia. The incidence of psychotic symptoms without dementia was 1.3%. Recent widows and farmers/breeders/craftsmen, versus public servants/teachers/executives, had both six times the odds of experiencing psychotic symptoms without dementia. Hearing impairment and the number of health conditions also increased the odds while increased age was protective.

Conclusion

Psychotic symptoms unrelated to dementia constitute a considerable mental health problem in old age. Paranoid delusions were the most prevalent. Socio-economic and health status factors are significant predictors of psychotic symptoms.

中文翻译：

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HELIAD 希腊社区老年人研究中与精神病症状存在相关的因素

摘要

背景

与老年人精神病症状相关的患病率和相关因素尚未得到充分研究。目的是评估具有代表性的希腊社区老年人样本中与精神病症状相关的患病率、发病率和因素。

方法

样本包括希腊拉里萨市和马鲁西市的n  = 1,904 名居民，他们参与了希腊老龄化和饮食纵向调查研究，基线时有可用数据， 3 年随访时有n = 947 人。根据哥伦比亚大学阿尔茨海默病精神病理学量表的 17 种症状和神经精神病学问卷调查的 14 种症状，评估过去一个月是否存在妄想和幻觉。神经科医生对可能诊断为痴呆和身体合并症进行了全面的神经心理学评估。惩罚逻辑回归分析用于评估与精神病症状相关的社会经济和临床因素。

结果

排除痴呆病例后，过去一个月精神病症状的患病率分别为 1.9% 和 1.0%。排除痴呆后，任何妄想和幻觉的发生率分别为 0.8% 和 0.3%。没有痴呆的精神病症状的发生率为1.3%。最近的寡妇和农民/饲养员/工匠，与公务员/教师/行政人员相比，出现精神病症状但没有痴呆的几率是两者的六倍。听力障碍和健康状况的数量也增加了几率，而年龄的增加具有保护作用。

结论

与痴呆症无关的精神病症状构成了老年时相当大的心理健康问题。偏执妄想是最普遍的。社会经济和健康状况因素是精神病症状的重要预测因素。