In this study, alpha and gamma iron oxide nanoparticles, characterizations, toxic effects after being exposed to rainbow trout (Oncorhynchus mykiss) at 0, 1, 10 and 25 mg/L concentrations for 10 days, and then 10-day recovery period without any nanoparticle exposure were examined for histopathological (kidney, liver and gill), hematological, iron accumulation and potential for oxidative stress (TBARS and GSH). Histopathological damages significant at the exposure of increasing concentrations of both nanoparticles (increase in melanomacrophage aggregations, epithelial tissue deformations, cytoplasmic vacuolizations, fatty changes, necrosis, pyknosis, hyperplasia, hypertrophy, lamellar fusions, capillary dilatations). Gamma nanoparticles were determined to accumulate more than the alpha nanoparticles. The most Fe accumulation was detected in the liver. The findings of oxidative stress parameters showed that both nanoparticles have the potential to generate oxidative stress. It was concluded that the exposure of alpha and gamma nanoparticles at specified concentrations and durations had a toxic effect on rainbow trout and the toxicity of these nanoparticles was similar.

在这项研究中，α和γ氧化铁纳米颗粒，特征，暴露于虹鳟鱼后的毒性作用（Oncorhynchus mykiss）在0、1、10和25 mg / L浓度下连续10天，然后在没有任何纳米颗粒暴露的情况下恢复10天，检查其组织病理学（肾脏，肝脏和g），血液学，铁蓄积和氧化应激的潜力（ TBARS和GSH）。随着两种纳米颗粒浓度的增加（黑素巨噬细胞聚集增加，上皮组织变形，细胞质空泡化，脂肪变化，坏死，肥大，增生，肥大，板层融合，毛细血管扩张），组织病理学损害显着。确定γ纳米颗粒比α纳米颗粒积累更多。在肝脏中检测到最多的铁积累。氧化应激参数的发现表明，两种纳米颗粒均具有产生氧化应激的潜力。