Efficient C4-arylation and domino C4-arylation/3,2-carbonyl migration of indoles have been developed. The former route enables C4-arylation in a highly efficient and mild manner and the latter route provides an alternative straightforward protocol for synthesis of C2/C4 disubstituted indoles. The mechanism studies imply that the different reaction pathways were tuned by the distinct acid additives, which led to either the Pd(I)–Pd(II) pathway or Pd(II) catalysis.

中文翻译：

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通过调节Pd催化模式：吲哚的C4-芳基化和多米诺C4-芳基化/ 3,2-羰基迁移：Pd（I）–Pd（II）催化与Pd（II）催化

已经开发了吲哚的有效的C4-芳基化和多米诺C4-芳基化/ 3,2-羰基迁移。前一种途径能够以高效和温和的方式实现C4-芳基化，后一种途径提供了合成C2 / C4二取代的吲哚的另一种直接方法。机理研究表明，不同的反应途径受不同的酸添加剂调节，从而导致Pd（I）–Pd（II）途径或Pd（II）催化。