Advances in embryo and reproductive genetics have influenced clinical approaches to overcome infertility. Since the 1990s, many attempts have been made to decipher the genetic causes of infertility and to understand the role of chromosome aneuploidies in embryo potential. At the embryo stage, preimplantation genetic testing for chromosomal abnormalities and genetic disorders has offered many couples the opportunity to have healthy offspring. Recently, the application of new technologies has resulted in more comprehensive and accurate diagnoses of chromosomal abnormalities and genetic conditions to improve clinical outcome. In this Special Issue, we include a collection of reviews and original articles covering many aspects of embryo diagnosis, genome editing, and maternal-embryo cross-communication during the implantation process.

中文翻译：

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胚胎遗传学

胚胎和生殖遗传学的进步影响了克服不孕症的临床方法。自 1990 年代以来，已经进行了许多尝试来破译不孕症的遗传原因并了解染色体非整倍体在胚胎潜力中的作用。在胚胎阶段，针对染色体异常和遗传疾病的植入前基因检测为许多夫妇提供了拥有健康后代的机会。最近，新技术的应用导致对染色体异常和遗传状况的更全面和准确的诊断，以改善临床结果。在本期特刊中，我们收录了一系列评论和原创文章，涵盖胚胎诊断、基因组编辑和植入过程中母体-胚胎交叉交流的许多方面。