Abstract

Radiation exposure is an on going and serious threat in military and public health concern. There is an unmet need for effective preventative or mitigative treatments against radiation-induced injuries. The handful of Food and Drug Administration in the US approved radiation protection agents cannot be widely used due to their side effects. Some natural nontoxic compounds such as bee products have been reported to prevent and treat radiation-induced injuries (e.g. scavenging free radicals, inhibiting cell apoptosis and reducing DNA damage), indicating that they may be a potential option as a safe radioprotective agent. Bee products are nontoxic and have no known side effects on the human body, and are effective in the field of radiation protection. They are expected to be interesting drug candidates for preventing and treating radiation-induced injuries. This article reviews the prevention and treatment of bee products on radiation-induced injuries.

摘要

辐射暴露是军事和公共卫生问题中持续存在的严重威胁。对针对辐射引起的损伤的有效预防性或缓解性治疗的需求未得到满足。美国食品和药物管理局批准的少数几种辐射防护剂由于其副作用而无法广泛使用。据报道，一些天然无毒化合物（如蜂产品）可预防和治疗辐射引起的损伤（例如清除自由基、抑制细胞凋亡和减少 DNA 损伤），表明它们可能是作为安全辐射防护剂的潜在选择。蜂产品无毒，对人体没有已知的副作用，在辐射防护领域有效。它们有望成为预防和治疗辐射损伤的有趣候选药物。本文就蜂产品对辐射损伤的防治作一综述。