BACKGROUND hemorrhagic cerebrovascular disease due to vascular malformations represents an emergency for neurosurgery and neuro-interventional departments. During the COVID-19 pandemic, a dramatic reduction in the number of hospitalizations for acute myocardial infarction or stroke and a larger time interval from symptom onset to first medical contact have been reported. This study aims to verify the hypothesis that there would also have been a reduction of admissions for hemorrhagic cerebrovascular disease during the Italian lockdown. MATERIAL AND METHOD s A multicenter, observational survey was conducted to collect data on hospital admissions for hemorrhagic cerebrovascular disease due to vascular malformations throughout two-months (March 15th to May 15th); the years 2020 (COVID-19 Italian lockdown), 2019 and 2018 were compared. Cases were identified by ICD-9 codes 430, 431, 432.1, 432.9, 747.81 of each hospital database. The statistical significance of the difference between the event rate of one year versus the others was evaluated using Poisson Means test, assuming a constant population. RESULTS During the 2020 lockdown, the total number of admissions for hemorrhagic cerebrovascular disease was 92 compared with 116 in 2019 and 95 in 2018. This difference was not significant. GCS upon admission was 3-8 in 44 % of cases in 2020 (41 patients), 39.7 % in 2019 (46 patients) and 28 % in 2018 (27 patients). CONCLUSION Reduction of admissions for hemorrhagic cerebrovascular disease due to vascular malformations during the COVID-19 lockdown was not confirmed. Nevertheless, some patients reached the emergency rooms only several days after symptoms onset, resulting in a worse clinical condition at admission.

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意大利 COVID-19 国家检疫期间血管畸形导致出血性脑血管病的发病率

背景技术血管畸形引起的出血性脑血管病是神经外科和神经介入科的急症。据报道，在 COVID-19 大流行期间，急性心肌梗塞或中风的住院人数急剧减少，从症状出现到首次就医的时间间隔更长。这项研究旨在验证以下假设：在意大利封锁期间，出血性脑血管疾病的入院人数也会减少。材料和方法 进行了一项多中心、观察性调查，以收集两个月（3 月 15 日至 5 月 15 日）因血管畸形导致的出血性脑血管病入院的数据；比较了 2020 年（COVID-19 意大利封锁）、2019 年和 2018 年。病例通过每个医院数据库的 ICD-9 代码 430、431、432.1、432.9、747.81 进行识别。假设人口不变，使用泊松均值检验评估一年事件率与其他事件率之间差异的统计显着性。结果 2020年封城期间，出血性脑血管病入院总人数为92人，2019年为116人，2018年为95人，差异不显着。2020 年 44% 的病例（41 名患者）、2019 年的 39.7%（46 名患者）和 2018 年的 28%（27 名患者）在入院时的 GCS 为 3-8。结论 在 COVID-19 封锁期间，由于血管畸形导致的出血性脑血管疾病住院人数减少尚未得到证实。然而，一些患者在症状出现几天后就到达了急诊室，