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Fabrication of titanium dioxide nanomaterial for implantable highly flexible composite bioelectrode for biosensing applications
Chemosphere ( IF 8.8 ) Pub Date : 2021-01-18 , DOI: 10.1016/j.chemosphere.2021.129680
Omnia Mohamed , Amani Al-Othman , Hasan Al-Nashash , Muhammad Tawalbeh , Fares Almomani , Mashallah Rezakazemi

Implantable and stretchable electrodes have managed to progress the medical field from a medical diagnosis aspect to a patient treatment level. They offer the ability to detect biosignals and conduct electrical current to tissues that aid in muscle stimulation and axon regeneration. Current conventional electrodes are fabricated from stiff and very expensive, precious metals such as platinum. In this work, novel, low cost, and highly flexible electrode materials were fabricated based on titanium dioxide (TiO2) and polymethyl methacrylate (PMMA) supported by a silicone polymer matrix. The electrode materials were characterized by their electrochemical, mechanical, and surface properties. The electrodes possessed high flexibility with Young’s modulus of 235 kPa, revealing highly stretchable characteristics. The impedance at 1 kHz was around 114.6 kΩ, and the charge capacity was 1.23 mC/cm2. The fabricated electrodes appeared to have a smooth surface, as seen in the scanning electron microscope micrographs, compared with electrodes in the literature. Long-time stability tests revealed an overall decrease in impedance and an increase in the charge capacity up to 475% of the initial value within three weeks.



中文翻译:

用于生物传感应用的可植入高柔性复合生物电极的二氧化钛纳米材料的制备

植入式和可伸展电极已经设法将医学领域从医学诊断方面发展到患者治疗水平。它们具有检测生物信号并向组织传导电流的能力,从而有助于肌肉刺激和轴突再生。当前的常规电极由坚硬且非常昂贵的贵金属例如铂制成。在这项工作中,新型,低成本,高柔性电极材料基于二氧化钛(TiO 2)和由有机硅聚合物基质支撑的聚甲基丙烯酸甲酯(PMMA)。电极材料的特征在于其电化学,机械和表面性能。电极具有较高的柔韧性,杨氏模量为235 kPa,具有高度可拉伸的特性。1 kHz时的阻抗约为114.6kΩ,充电容量为1.23 mC / cm 2。如在扫描电子显微镜显微照片中所见,与文献中的电极相比,所制造的电极似乎具有光滑的表面。长期稳定性测试表明,在三周内,阻抗总体下降,充电容量增加至初始值的475%。

更新日期:2021-01-22
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